Conolidine’s analgesic consequences stem from its conversation with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors during the central anxious procedure, conolidine modulates alternate molecular targets. A Science Improvements research found that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide avai... https://whatischronicpain12234.pages10.com/about-alternative-natural-pain-relief-to-replace-traditional-painkillers-73198245