Pentobarbital will decrease the level or effect of aprepitant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of meloxicam by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of glecaprevir/pibrentasvir by affecting hepatic/intestinal... https://thejillist.com/story10623303/indicatori-sulla-pentobarbital-si-deve-sapere