Pentobarbital will decrease the level or effect of alfentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of amiodarone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital decreases effects of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 met... https://topsocialplan.com/story5888907/la-guida-pi%C3%B9-grande-per-ordinare-pentobarbital-di-sodio