You will find there's release of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors while in the dorsal horn to reduce afferent agony transmission and deliver analgesia. Hence, medicine like clonidine that target alpha-2 receptors can influence the transmission of soreness. Might be presented as monotherapy https://aleisterr850qmd4.blogitright.com/profile