Pentobarbital will lessen the extent or outcome of fedratinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Influence of coadministering a strong CYP3A4 inducer with fedratinib hasn't been examined. pentobarbital decreases amounts of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Solid CYP3A4 inducers ... https://is-nembutal-legal-in-usa06037.shotblogs.com/is-nembutal-a-depressant-an-overview-45041852